Clinical AI · Explainable by Design

We turn complex clinical workflows into
clear, explainable treatment options.

PEONOVA is an AI clinical decision engine that reads guidelines, verifies eligibility, and structures treatment plans.

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Trusted by practicing oncologists

Clinicians are spending their expertise on the wrong problems.

Every treatment decision involves a chain of work that should never require a specialist. Reading through 300-page guidelines. Cross-checking SmPC criteria drug by drug. Manually piecing together fragmented patient records. Verifying eligibility step by step. It's not clinical work. But it's consuming clinical time.

80% of the work surrounding a treatment decision is administrative, repetitive, and guideline-driven. That's not a workflow problem. That's a structural one.

Evolving Guidelines

Clinical guidelines change constantly. Tracking them manually across NCCN, ESMO, EAU, and national frameworks is unsustainable at scale.

SmPC Complexity

Every drug has its own eligibility criteria, contraindications, and reimbursement rules. Verifying them takes time clinicians don't have.

Fragmented Records

Patient data lives across discharge summaries, lab results, and imaging reports that are unstructured, scattered, and time-consuming to synthesize.

Long-term Care Burden

Chronic disease care doesn't end at the treatment plan. Monitoring, dose adjustments, and follow-up scheduling add compounding administrative load over months and years.

AI that shows its work.

In healthcare, trust is not optional. A clinician won't act on a recommendation they can't trace. An institution won't adopt a system they can't audit. A regulator won't approve a black box.

We built PEONOVA on one principle: every output must be explainable. Not just what the system recommends — but which guideline rule was applied, which SmPC criterion was evaluated, and which patient data point triggered the logic. That's not a feature. That's the foundation.

Black Box AI

  • Outputs a recommendation
  • Probabilistic
  • Clinicians trust blindly or not at all
  • Hard to certify for medical use

PEONOVA

  • Shows every reasoning step
  • Deterministic and auditable
  • Clinicians verify, then decide
  • Built for regulatory compliance

From complexity to clarity in four steps.

PEONOVA doesn't replace clinical judgment. It structures everything around it.

Step 01

From guidelines to ranked options with reasoning.

PEONOVA ingests published clinical guidelines (NCCN, ESMO, EAU, national protocols) and converts them into structured logic. For each patient case, it generates all eligible treatment options, ranks them by suitability, and explains why each applies or doesn't.

Option A: Preferred Regimen 98% match
Full guideline alignment • ECOG 0-1
Option B: Alternative 82% match
Conditional alignment • Dose adjustment needed
Option C: Not Recommended 45%
Contraindicated by comorbidities
Renal Function CrCl > 30 ml/min — Current: 42 ml/min
Prior Exposure Verification Naïve to therapy class
Interaction Risk Review concomitant medication flagged
Step 02

Every drug requirement, verified step by step.

Combined with treatment options, PEONOVA walks through every SmPC criterion indication alignment, contraindications, drug interactions, reimbursement rules. What typically takes hours of cross-referencing takes minutes. Flags are instant. Documentation is automatic.

Step 03

A plan that's ready to act on.

PEONOVA assembles the clinical decision into a structured, reviewable treatment plan with guideline citations, eligibility assessments, and documented reasoning. Built for the clinician to approve, not to second-guess.

Treatment Execution Plan v1.2 Approved
Phase 1: Induction
60% Progress
Guideline Justification Documented
Patient Consent Ready
Labs & Diagnostics Scheduled Day 1
Toxicity Monitoring Weekly assessment required
Dose Adjustment Pending lab results
Step 04

Chronic disease care doesn't end at the plan.

For chronic conditions, PEONOVA generates a living task timeline from guidelines and SmPC rules monitoring schedules, lab requirements, dose adjustment triggers, and follow-up milestones. The complexity stays inside the system. The clinician sees clear next steps and recommendations.

Key Outcomes

Clearer and faster decisions

Complex cases resolved into evidence-ranked options in minutes, not hours of manual work.

Every step traceable

Every option, plan, and action links back to the guideline section or SmPC rule that justified it.

Confidence through transparency

Clinicians see the reasoning behind every recommendation. Explainable AI they can verify and trust.

Consistency across the journey

Reduces clinical variability in long-term treatment pathways across patients, practitioners, and institutions.

Less admin. More care.

PEONOVA handles the guideline complexity. Clinicians focus on the patient.

The same engine. An unlimited number of conditions.

We started where the complexity is hardest - cancer. If the engine can handle it there, it can handle it anywhere. Cancer is the starting point. All of medicine is the scale.

Iceberg Model Iceberg Model
Cancer Care

Prostate cancer first. Then lung, kidney, breast, colorectal. The hardest test we could find. The engine passed.

Chronic Care

Same engine. New guidelines loaded. The conditions consuming 80% of global healthcare spend, all addressable.

All Guideline-Driven Medicine

Every condition with a guideline is within reach. The zeros on the right are not a gap. They're where we're headed.

One Engine,
Infinite Applications.

Come see what we've built.

The engine is live, the reasoning is visible, and the impact on clinical time is real. We'd love to show you.

Request a Demo
No commitment. 30 minutes. See the product in a real clinical scenario.